Potential new treatment for gastrointestinal cancers discovered
(Medical Xpress)—Researchers have identified a complex of proteins that promotes the growth of some types of colon and gastric cancers, and shown that medications that block the function of this...
View ArticleNew insight into RASopathy-associated lymphatic defects
The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.
View ArticleTube versus IV feeding in malnourished pediatric cancer patients
About 60 percent of pediatric cancer patients experience malnourishment during treatment. At that point, patients and families have a choice: tube feeding or IV nutrition supplement. Which would you...
View ArticleGene discovery reveals importance of eating your greens
(Medical Xpress)—Eating your greens may be even more important that previously thought, with the discovery that an immune cell population essential for intestinal health could be controlled by leafy...
View ArticleEngineering and autism: Chemical engineer investigates autism spectrum disorders
(Medical Xpress)—The University of Delaware's Prasad Dhurjati is a chemical engineer whose background includes systems engineering, biotechnology and artificial intelligence. Yet recently, he has been...
View ArticleFinding a new way to manage infections
(Medical Xpress)—Waging an immunological war against a pathogen is not the body's only way to survive an infection. Sometimes tolerance, or learning to live with an invader, can be just as important....
View ArticleClearing the BAR to oral vaccines
A new technology under development by an academic–industry partnership protects oral vaccines from destruction by the digestive system.
View ArticleBariatric surgery restores nerve cell properties altered by diet
Understanding how gastric bypass surgery changes the properties of nerve cells that help regulate the digestive system could lead to new treatments that produce the same results without surgery,...
View ArticleThe four-point test to predict death risk from C. difficile
A Clostridium difficile (C. diff) infection is one that can affect the digestive system and most commonly affects people staying in hospital. It is not generally a problem for healthy people but may...
View ArticleOpening up new pathways for treating inflammatory bowel diseases
Inflammatory bowel disease (IBD) is a chronic condition affecting 1 in 250 people in Europe. Current treatment is ineffective for many. However, a team of European scientists has increased...
View ArticleGastric bypass surgery changes the brains response to food
(Medical Xpress)—The weight loss seen in patients after gastric bypass surgery for obesity may be helped by changes in the way the brain itself responds to food, reducing not only hunger but also the...
View Article105 additional genetic errors that cause cystic fibrosis pinpointed
Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis (CF), it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers...
View ArticleGut bugs may hold key to weight control, mouse study suggests
(HealthDay)—The bacteria living in your digestive system may be the last thing on your mind, but a new study in mice raises the prospect that obese people might get benefits through the transfer of a...
View ArticleProton pump inhibitors linked to disruption of gut microbiome
(HealthDay)—Proton pump inhibitors may disrupt the microbiome of the digestive system, leading to infections and other complications, according to a small new study published online Nov. 25 in Microbiome.
View ArticleMetabolic disease and obesity may be caused by abnormal behavior of gut bacteria
(Medical Xpress)—Taking a single snapshot of all the bacteria that live in a mouse's–or person's–stomach and intestines can capture the health of the organism's digestive system and even their risk of...
View ArticleMental disorders and physical diseases co-occur in teenagers
Every third teenager has suffered from one mental disorder and one physical disease. These co-occurrences come in specific associations: More often than average, depression occurs together with...
View ArticleTeam discovers how cells distinguish friend from foe
(Medical Xpress)—Researchers at UC Davis have shown how the innate immune system distinguishes between dangerous pathogens and friendly microbes. Like burglars entering a house, hostile bacteria give...
View ArticleBrain-building gene plays key role in gut repair
(Medical Xpress)—A gene with a colorful name – mindbomb 1 – plays a key role far beyond the brain. New research at Washington University School of Medicine in St. Louis shows that mindbomb 1 may be...
View ArticleBiomarkers discovered for inflammatory bowel disease
Using the Department of Defense Serum Repository (DoDSR), University of Cincinnati (UC) researchers have identified a number of biomarkers for inflammatory bowel disease (IBD), which could help with...
View ArticleFemales fend off gut diseases
At least among mice, females have innate protection from certain digestive conditions, according to a new Michigan State University study.
View ArticleMother's asthma during pregnancy may raise child's health risks
(HealthDay)—A large new study of Danish women has tied a mother's asthma during pregnancy to a higher risk for developing a wide range of childhood diseases among her offspring.
View ArticleNew insights into the immune system of the gastrointestinal tract
Lymphotoxin is a cytokine, or intercellular messenger, and plays an important role in the immunological balance of the gastrointestinal tract. It regulates the immune system of the digestive tract,...
View ArticleImmune cell's role in intestinal movement may lead to better understanding of...
(Medical Xpress)—Learning the role of immune-system cells in healthy digestive tracts and how they interact with neighboring nerve cells may lead to new treatments for irritable bowel syndrome (IBS)....
View ArticleThe impact of bacteria in our guts
The word metabolism gets tossed around a lot, but it means much more than whether you can go back to the buffet for seconds without worrying about your waistline. In fact, metabolism is the set of...
View ArticleWorms and germs lead to better immune function
A growing body of evidence in the medical community holds that greater diversity of bacteria and even worms in the digestive tract offers protection against a variety of allergic and autoimmune problems.
View ArticlePioneering study may explain the origin of several digestive diseases
There are numerous studies related to the absorption of nutrients from the stomach since understanding what happens in our digestive system is crucial, for example, in order to be able to avoid certain...
View ArticleTissue-engineered colon from human cells develop different types of neurons
A study by scientists at Children's Hospital Los Angeles has shown that tissue-engineered colon derived from human cells is able to develop the many specialized nerves required for function, mimicking...
View ArticleNew findings on the connections between gut microbiota and the brain
Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the "gut-brain axis" for neurology and indicates that the...
View ArticleFood's transit time is a key factor in digestive health
The time it takes for ingested food to travel through the human gut – also called transit time – affects the amount of harmful degradation products produced along the way. This means that transit time...
View ArticleOct4 found to be a prognostic marker for digestive cancers
(HealthDay)—Octamer-binding transcription factor 4 (Oct4) is a predictive marker for patients with digestive system cancers, according to a review and meta-analysis published online Nov. 7 in the...
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